"Now we have a background noise modeling framework that can distinguish between deviations in tumor sequencing data that arise due to inherent noise versus those that arise due to real copy-number ...

In a way, sequencing DNA is very simple: There's a molecule, you look at it, and you write down what you find. You'd think it would be easy—and, for any one letter in the sequence, it is. The problem ...

Long-read sequencing technologies analyse long, continuous stretches of DNA. These methods have the potential to improve researchers’ ability to detect complex genetic alterations in cancer genomes.

The PRRDetect algorithm identifies hidden DNA repair flaws in tumors It helps doctors choose effective therapies based on the tumor’s genetics This advancement brings personalized cancer care closer ...

April 14, 2025 – Genome Research (https://genome.org) publishes a second special issue highlighting advances in long-read sequencing applications in biology and medicine. In this second Special Issue, ...

Genome sequencing has been a cornerstone of genomics research and personalized medicine, enabling the detailed mapping of genetic information. However, the completeness and accuracy of human genome ...

Researchers at EMBL’s European Bioinformatics Institute (EMBL-EBI) have developed a new machine learning method called SAVANA that significantly reduces sequencing errors for cancer genomes.

TEL AVIV, Israel & LEHI, Utah & HOUSTON & FREMONT, Calif.--(BUSINESS WIRE)--MyHeritage, the leading global platform for family history and DNA testing, announced today a landmark move to Whole Genome ...