Complement activation protects against infection but also contributes to pathological mechanisms in a range of clinical conditions such as autoimmune diseases and transplant rejection.
The classical complement pathway is an important effector mechanism for clearance of infections, which is also employed in immunotherapies to eliminate tumor cells. Its initiation is governed by the ...
The complement system is an essential component of our innate defense and plays a vital role in the pathogenesis of many diseases. Assessment of complement activation is critical in monitoring both ...
The complement system, originally classified as part of innate immunity, is a tightly self-regulated system consisting of liquid phase, cell surface, and intracellular proteins. In the blood ...
Complement 3 glomerulopathy (C3G) is a rare kidney disease that affects your body’s innate immune system (complement system). Complement 3 glomerulopathy (C3G) is a kidney disease that’s caused by ...
Bryan Paul Morgan is a consultant for UCB Pharma and has provided ad hoc advice to other Pharma comanies. He receives funding from UK Medical Research Council via the Dementia Research Institut, ...
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